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Manager/ Sr. Scientist

Company: (BMS) Bristol-Myers Squibb
Location: Jersey City
Posted on: June 29, 2020

Job Description:

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. POSITION Manager/Sr. Scientist, Downstream Process Development SUPERVISOR Director, Downstream Process Development DEPARTMENT Biologics Development Prerequisites: Ph.D. in Chemical/Biochemical Engineering, Biochemistry, Biophysics or equivalent with a minimum of 6+ years of industry and/or academic experience. The Manager/Senior Scientist position will be in the Downstream Process Development group in Summit, NJ and be responsible for the development of scalable purification process, process characterization, Tox material production, and tech transfer to GMP facilities for clinical/commercial manufacturing. Specifically, this person will lead a team to develop downstream processes, covering all downstream unit operations (i.e., recovery, centrifugation, chromatography, depth filtration, viral filtration, ultrafiltration/diafiltration, etc.). The candidate will drive platform purification process strategies, and technology development projects. In addition, the candidate will actively partner with the overall Downstream team, Upstream team, Cell-line development team, Manufacturing, MS&T, Analytical Development, Formulation Development, Project Management, and R&D groups. This candidate will also present and report results to senior leadership within the Biologics Process Development organization. RESPONSIBILITIES WILL INCLUDE, BUT ARE NOT LIMITED TO, THE FOLLOWING: * Design, execution and data interpretation of laboratory experiments as well as providing guidance to team members. * Certain amount on hands-on operation of equipment needed for downstream process development. * Execute process optimization, scale up and tech transfer to internal or external manufacturers for GMP production * Prepare/review technical documents including development /tech transfer reports, process characterization reports, batch records, SOPs and CMC regulatory submissions. * Participate on cross-functional teams to progress both early and late stage drug candidates. * Expand the technical capabilities of the Process Development group, by keeping abreast of new development and introducing new technologies as well as perform/guide the necessary experiments for evaluation and implementation. SKILLS/KNOWLEDGE REQUIRED: * Ph.D. in Chemical/Biochemical Engineering, Biochemistry, Biophysics or equivalent with a minimum of 6+ years of industry and/or academic experience. * In depth understanding and prior experience in downstream process development * Managerial experience as well as the ability to lead matrix teams * Knowledge of statistical experimental design and data analysis. * Knowledge of new purification technologies, and analytical techniques. * Knowledge of cGMPs as applied to process development and scale up. * Ability to work collaboratively in a team and matrix environment * Excellent oral and written communication skills Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Keywords: (BMS) Bristol-Myers Squibb, Jersey City , Manager/ Sr. Scientist, Executive , Jersey City, New Jersey

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